The blast occurred in a residential area in the Guwarsha district, the scene of fighting between security forces loyal to Libya’s eastern government and an alliance of Islamists and other opponents.
A witness told the Reuters news agency the powerful explosion reduced a three-story building to rubble.
Benghazi has witnessed fierce battles in the past two years between pro-government troops led by Haftar and armed militias, including Takfiri groups such as Daesh (ISIS/ISIL) and the al-Qaeda-linked Ansar al-Sharia.